Criteria to predict carriers of a novel SCN5A mutation in a large Portuguese family affected by the Brugada syndrome

Santos, L. F.Rodrigues, B.Moreira, D.Correia, E.Nunes, L.Costa, A.Elvas, L.Pereira, T.Machado, J. C.Castedo, S.Henriques, C.Matos, A.Santos, J. O.2017-02-032017-02-032012Santos, L. F., Rodrigues, B., Moreira, D., Correia, E., Nunes, L., Costa, A., Elvas, L., Pereira, T., Machado, J. C., Henriques, C., Matos, A. & Santos, J. O. (2012). Criteria to predict carriers of a novel SCN5A mutation in a large Portuguese family affected by the Brugada syndrome. Europace, 14(6), 882–8http://hdl.handle.net/10400.19/4382Brugada syndrome (BrS) is a life-threatening arrhythmia disorder associated with autosomal-dominant mutations in the SCN5A gene. We aimed to characterize the diagnostic challenges and clinical manifestations of a novel SCN5A mutation associated with BrS.engBrugada SyndromeSCN5A mutationECGSAECGDiagnostic criteriaSudden cardiac deathCriteria to predict carriers of a novel SCN5A mutation in a large Portuguese family affected by the Brugada syndromejournal article10.1093/europace/eur421