Browsing by Author "Nunes, L."
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- Criteria to predict carriers of a novel SCN5A mutation in a large Portuguese family affected by the Brugada syndromePublication . Santos, L. F.; Rodrigues, B.; Moreira, D.; Correia, E.; Nunes, L.; Costa, A.; Elvas, L.; Pereira, T.; Machado, J. C.; Castedo, S.; Henriques, C.; Matos, A.; Santos, J. O.Brugada syndrome (BrS) is a life-threatening arrhythmia disorder associated with autosomal-dominant mutations in the SCN5A gene. We aimed to characterize the diagnostic challenges and clinical manifestations of a novel SCN5A mutation associated with BrS.
- Life Cycle Assessment as a tool to promote sustainable Thermowood boards: a Portuguese case studyPublication . Ferreira, J.; Esteves, B.; Nunes, L.; Domingos, I.The present work aims to develop the Life Cycle Assessment study of thermo-modified Atlanticwood® pine boards based on real data provided by Santos & Santos Madeiras company. Atlanticwood® pine boards are used mainly for exterior decking and cladding facades of buildings. The LCA study is elaborated based on ISO 14040/44 standard and Product Category Rules for preparing an environmental product declaration for Construction Products and Construction Services. The inventory analysis and, subsequently, the impact analysis have been performed using the LCA software SimaPro8.0.4. The method chosen for impact assessment was EPD (2013) V1.01. The results show that more than ¾ of ‘Acidification’, ‘Eutrophication’, ‘Global warming’ and ‘Abiotic depletion’ caused by 1 m3 of Atlanticwood® pine boards production is due to energy consumption (electricity + gas + biomass). This was to be expected since the treatment is based on heat production and no chemicals are added during the heat treatment process.
- Prospective study on spontaneous fluctuations between diagnostic and non-diagnostic ECGs in Brugada syndrome screeningPublication . Matos, Ana; Henriques, Carla; Santos, Luís; Correia, E.; Rodrigues, B.; Faria, R.; Nunes, L.; Costa, A.; Carvalho, J.; Santos, J.
- Termite resistance, chemical and mechanical characterization of paulownia tomentosa wood before and after heat treatmentPublication . Esteves, Bruno; Ferreira, Helena; Viana, Helder Filipe dos Santos; Ferreira, José; Domingos, Idalina; Cruz-Lopes, Luísa; Jones, D.; Nunes, L.The introduction of new species in forest management must be undertaken with a degree of care, to help prevent the spread of invasive species. However, new species with higher profitability are needed to increase forest products value and the resilience of rural populations. Paulownia tomentosa has an extremely fast growth. The objective and novelty of this work was to study the potential use of young Paulownia trees grown in Portugal by using heat treatment to improve its properties, thereby allowing higher value applications of the wood. The average chemical composition of untreated and heat-treated wood was determined. The extractive content was determined by successive Soxhlet extraction with dichloromethane (DCM), ethanol and water as solvents. The composition of lipophilic extracts was performed by injection in GC-MS with mass detection. Insoluble and soluble lignin, holocellulose and α-cellulose were also determined. Physical (density and water absorption and dimensional stability) and mechanical properties (bending strength and bending stiffness) and termite resistance was also determined. Results showed that extractive content increased in all solvents, lignin and α-cellulose also increased and hemicelluloses decreased. Compounds derived from the thermal degradation of lignin were found in heat-treated wood extractions. Dimensional stability improved but there was a decrease in mechanical properties. Resistance against termites was better for untreated wood than for heat-treated wood, possibly due to the thermal degradation of some toxic extractives.