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Exploiting Codon-Triplets Association for Genome Primary Structure Analysis

dc.contributor.authorLousado, José
dc.contributor.authorOliveira, José
dc.contributor.authorMoura, Gabriela
dc.contributor.authorSantos, Manuel
dc.date.accessioned2012-04-10T15:51:07Z
dc.date.available2012-04-10T15:51:07Z
dc.date.issued2008
dc.description.abstractAbstract— The way evolution shapes the arrangement of synonymous codons within open reading frames (ORF) for fine tuning mRNA decoding efficiency is not yet understood. Since the ribosome has 3 tRNA binding sites, the context of triplets should be relevant to decoding fidelity and efficiency. We have developed a software application for large-scale analysis of codon-triplet associations to shed new light into this problem. The developed algorithms identify codon-triplets context biases, allowing for large scale comparative codon-triplet analysis and for identification of alterations to the standard genetic code.por
dc.identifier.isbn978-0-7695-3191-5
dc.identifier.urihttp://hdl.handle.net/10400.19/1065
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherIEEE Computer Societypor
dc.subjectBioinformaticspor
dc.subjectcomparative genomicspor
dc.subjectdata miningpor
dc.titleExploiting Codon-Triplets Association for Genome Primary Structure Analysispor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceBucareste, Roméniapor
oaire.citation.endPage158por
oaire.citation.startPage155por
oaire.citation.titleInternational Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, 2008. BIOTECHNO '08por
person.familyNameFERREIRA LOUSADO
person.givenNameJOSÉ PAULO
person.identifier.ciencia-id671E-8E27-5F20
person.identifier.orcid0000-0002-5757-5441
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublication954e0a43-4745-4db8-b97f-6207e4389c5f
relation.isAuthorOfPublication.latestForDiscovery954e0a43-4745-4db8-b97f-6207e4389c5f

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