Publicação
Exploiting Codon-Triplets Association for Genome Primary Structure Analysis
| dc.contributor.author | Lousado, José | |
| dc.contributor.author | Oliveira, José | |
| dc.contributor.author | Moura, Gabriela | |
| dc.contributor.author | Santos, Manuel | |
| dc.date.accessioned | 2012-04-10T15:51:07Z | |
| dc.date.available | 2012-04-10T15:51:07Z | |
| dc.date.issued | 2008 | |
| dc.description.abstract | Abstract— The way evolution shapes the arrangement of synonymous codons within open reading frames (ORF) for fine tuning mRNA decoding efficiency is not yet understood. Since the ribosome has 3 tRNA binding sites, the context of triplets should be relevant to decoding fidelity and efficiency. We have developed a software application for large-scale analysis of codon-triplet associations to shed new light into this problem. The developed algorithms identify codon-triplets context biases, allowing for large scale comparative codon-triplet analysis and for identification of alterations to the standard genetic code. | por |
| dc.identifier.isbn | 978-0-7695-3191-5 | |
| dc.identifier.uri | http://hdl.handle.net/10400.19/1065 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | IEEE Computer Society | por |
| dc.subject | Bioinformatics | por |
| dc.subject | comparative genomics | por |
| dc.subject | data mining | por |
| dc.title | Exploiting Codon-Triplets Association for Genome Primary Structure Analysis | por |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Bucareste, Roménia | por |
| oaire.citation.endPage | 158 | por |
| oaire.citation.startPage | 155 | por |
| oaire.citation.title | International Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, 2008. BIOTECHNO '08 | por |
| person.familyName | FERREIRA LOUSADO | |
| person.givenName | JOSÉ PAULO | |
| person.identifier.ciencia-id | 671E-8E27-5F20 | |
| person.identifier.orcid | 0000-0002-5757-5441 | |
| rcaap.rights | openAccess | por |
| rcaap.type | conferenceObject | por |
| relation.isAuthorOfPublication | 954e0a43-4745-4db8-b97f-6207e4389c5f | |
| relation.isAuthorOfPublication.latestForDiscovery | 954e0a43-4745-4db8-b97f-6207e4389c5f |