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Advisor(s)
Abstract(s)
Over the last 30 years the combination of both a sedentary lifestyle and excessive food availability has led to a significant increase
in the prevalence of obesity and aggravation of rates of metabolic syndrome and type 2 diabetes mellitus (T2DM). Several lines
of scientific evidence have been demonstrating that a low level of physical activity and decreased daily energy expenditure leads
to the accumulation of visceral fat and, consequently, the activation of the oxidative stress/inflammation cascade, which underlies
the development of insulin resistant T2DM and evolution of micro, and macrovascular complications. This paper focuses on the
pathophysiological pathways associated with the involvement of oxidative stress and inflammation in the development of T2DM
and the impact of regular physical exercise (training) as a natural antioxidant and anti-inflammatory strategy to prevent evolution
of T2DM and its serious complications.
Description
Keywords
Oxidative Stress Inflammation Type 2 DiabetesMellitus T2DM Physical Exercise Antioxidant
Citation
Teixeira de Lemos, E., Oliveira, J., Páscoa Pinheiro, J., and Reis, F. (2012). Regular Physical Exercise as a Strategy to Improve Antioxidant and Anti-Inflammatory Status: Benefits in Type 2 Diabetes Mellitus. Oxidative Medicine and Cellular Longevity, vol. 2012, Article ID 741545, 15 pages
Publisher
Hindawi Publishing Corporation