Browsing by Author "Ortiz, A."
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- Evaluation of small intestine apoptosis after haemorrhage followed by volume replacement – a preliminary studyPublication . Ortiz, A.; Vala, Helena; Garcia, C.; Cruz, R.; Venâncio, C.; Silva, A.; Ferreira, D.Apoptosis plays a key role in intestinal injury, as response to ischemia. Furthermore, reperfusion exacerbates abnormal intestinal apoptosis. In this study, the apoptotic index (AI) in the small intestine after haemorrhage and volume replacement with Ringer´s solution was evaluated, in a pig model
- Histological evaluation of the spleen after acute bleeding followed by volume replacement with two different physiologic solutionsPublication . Cabral, M.; Ortiz, A.; Venâncio, C.; Mesquita, J.; Nóbrega, C.; Silva, A.; Vala, Helena; Ferreira, D.Spleen is important for many hematopoietic and immunological functions, namely in hemodynamic compensation during hemorrhagic shock, with a crucial role in restoring blood volume in situations of acute haemorrhage. Also, the administration of physiological solutions is of great importance for the correction of circulating volume, avoiding complications due to hypovolemia. The aim of this study was to evaluate spleen`s histopathological changes, associated with volume replacement using two different physiologic solutions (Hydroxyethyl Starch (HES) 130/0.4 and Ringer Lactate), after acute controlled bleeding, in a pig model.
- Renal apoptosis signalling in a pig haemorrhagic model, after volume replacement with HES 130/0.4 or Ringer solutionPublication . Cruz, R.; Vala, Helena; Machado, A.; Venâncio, C.; Mesquita, Jr; Silva, A.; Ortiz, A.; Ferreira, D.TUNEL staining is one of the most frequently used method to detect apoptosis in renal tissues. The aim of this part of the study was to evaluate kidney damage after acute bleeding and volume replacement, with a colloid or a crystalloid, in a pig model
- Small intestine apoptosis evaluation after haemorrhage followed by volume replacement with colloid and crystalloid solution in a pig modelPublication . Ortiz, A.; Vala, Helena; Garcia, C.; Cruz, R.; Venâncio, C.; Silva, A.; Ferreira, D.Apoptosis plays a key role in intestinal injury, as response to ischemia. Furthermore, reperfusion exacerbates abnormal intestinal apoptosis. In this study, the apoptotic index (AI) in the small intestine after haemorrhage and volume replacement with Ringer´s solution was evaluated, in a pig model