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Prehospital therapeutic hypothermia : influence in good neurological outcome at hospital discharge

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dc.contributor.authorMarques, Nuno
dc.contributor.authorCunha, Madalena
dc.contributor.authorAlves, Mónica
dc.contributor.authorSantos, Eduardo
dc.date.accessioned2017-01-23T10:01:48Z
dc.date.available2020-09-01T00:30:11Z
dc.date.issued2016
dc.date.updated2016-12-15T21:42:40Z
dc.description.abstractIntroduction: Therapeutic hypothermia improves neurological outcomes after Out-of-Hospital Cardiac Arrest (OHCA). Its use has been recommended in the victims with Return of Spontaneous Circulation (ROSC). Objectives: The aim of this study was to know the effect of Prehospital Therapeutic Hypothermia (PHTH) on the neurological outcomes in victims with OHCA. Methods: We conducted a Systematic Review of Literature (SRL) on studies that evaluated the effect of HTPH in victims with OHCA and also performed a research (in PUBMED, EBSCO and Google Scholar) in studies published between January 2007 and 31 May 2013. The studies found were then assessed taking into account the previously established inclusion criteria. The quality of the studies included was assessed by two reviewers using the critical evaluation scale of a study describing a prospective, randomized, controlled clinical trial (RCT) by Carneiro (2008). The meta-analysis was performed using the Mantel-Haenszel method, using the effect of random models. Results: Five RCT's that respect the inclusion criteria were used, involving 759 participants from which 378 were selected from the prehospital hypothermia group and 381 from the control group. The studies show that there are not significant differences observed with respect to the neurological outcomes favorable at discharge (RR = 0.98; 95% CI = 0.79 to 1.20; p = 0.83). Conclusions: Despite SRL show that PHTH has no influence on the neurological outcome at hospital discharge, the scientific evidence points to an improvement in neurologic outcomes when kept at normothermia, so suggests a prompt reference to health units where can be made a control of temperature in the victims with ROSC in prehospital.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier0212-6567en_US
dc.identifier.citationMarques, N., Cunha, M., Alves, M., & Santos, E. (2016). Prehospital therapeutic hypothermia: Influence in good neurological outcome at hospital discharge. Atención Primaria, 48(Espec Cong 1), 106.pt_PT
dc.identifier.issn0212-6567
dc.identifier.urihttp://hdl.handle.net/10400.19/4073
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationFCT, IPV, CI&DETSpt_PT
dc.relation.publisherversionhttp://www.elsevier.es/re-revista-atencion-primaria-27-articulo-oral-communications-X0212656716593638pt_PT
dc.subjectTherapeutic hypothermiapt_PT
dc.subjectCardiac arrestpt_PT
dc.subjectPrehospitalpt_PT
dc.titlePrehospital therapeutic hypothermia : influence in good neurological outcome at hospital dischargept_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceEspanhapt_PT
oaire.citation.endPage106pt_PT
oaire.citation.startPage106pt_PT
oaire.citation.titleAtención Primariapt_PT
oaire.citation.volume48(Espec Cong 1)pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT

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