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OvisOme: atualização da base de dados de Ovis aries

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dc.contributor.authorEsteves, E.
dc.contributor.authorFernandes, M.
dc.contributor.authorRosa, N.
dc.contributor.authorCorreia, M. J.
dc.contributor.authorVala, Helena
dc.contributor.authorBarros, M.
dc.date.accessioned2016-06-06T08:23:40Z
dc.date.available2016-06-06T08:23:40Z
dc.date.issued2016
dc.description.abstractIntroduction: The Omics sciences are part of the research and diagnostic routines in human health. However, their application in veterinary sciences is still sparse, albeit the increasing number of proteomics studies published, especially regarding farm animals. The amount of information accumulated by these high throughput techniques, makes the existence of specialized databases fundamental. These databases are essential to store, annotate and make available to the scientific community, all the information gathered by the different omics studies, so that researchers can use it to understand the physio pathological mechanisms underlying sheep diseases, as well as to develop new and improved diagnostic, prognostic and therapeutic strategies. Objetive: The aim of this work is to present the OvisOme database and to demosntrate how it can be used to understand the molecular mechanisms urderlying sheep disease. Methodologies: OvisOme compiles all proteins identified by proteomics studies of Ovis aries. The proteins are annotated as to the sample characterization, the proteomics techniques used and all the data the authors refer regarding the donor sheep’s health. Results: The database currently has 1451 proteins, associated to 8 diseases and 10 breeds. When compared to other proteomics databases, the OvisOme stores and displays more information than other databases not specific for sheep, such as UniProt. Conclusion: OvisOme is a valuable tool for the study of the molecular mechanisms underlying sheep health and disease.pt_PT
dc.identifier.citationEsteves E, Fernandes M, Rosa N, Correia MJ, Vala H, Barros M (2016). OvisOme: atualização da base de dados de Ovis aries. Abstracts in Conference Proceedings of the XXI Meeting of the Portuguese Society of Animal Pathology. Beyond Routine Diagnosis: 39-40pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.19/3198
dc.language.isoengpt_PT
dc.relationCITAB; FCT (UID/AGR/04033/2013 and POCI-01-0145-FEDER-006958). CI&DETS, FCT, Ovislab ICT-2013-05-004-5314 ID-64757pt_PT
dc.subjectOvisOmept_PT
dc.subjectOvis ariespt_PT
dc.subjectdatabasept_PT
dc.subjectOmics sciencespt_PT
dc.subjectsheep diseasespt_PT
dc.titleOvisOme: atualização da base de dados de Ovis ariespt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.endPage40pt_PT
oaire.citation.startPage39pt_PT
oaire.citation.titleConference Proceedings of the XXI Meeting of the Portuguese Society of Animal Pathology. Beyond Routine Diagnosispt_PT
person.familyNameVala Correia
person.givenNameHelena Maria
person.identifier.ciencia-id7A1E-E85E-FFA4
person.identifier.orcid0000-0001-6829-4867
rcaap.rightsrestrictedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationcdc3d2e2-df06-40ed-8900-1ecbc8a06c8a
relation.isAuthorOfPublication.latestForDiscoverycdc3d2e2-df06-40ed-8900-1ecbc8a06c8a

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