Repository logo
 
Publication

Increased risk of hepatitis E virus infection in workers occupationally exposed to sheep

dc.contributor.authorMesquita, João
dc.contributor.authorSantos-Ferreira, Nanci
dc.contributor.authorFerreira, Ana S.
dc.contributor.authorAlbuquerque, Carlos
dc.contributor.authorNóbrega, Carmen
dc.contributor.authorEsteves, Fernando
dc.contributor.authorCruz, Rita
dc.contributor.authorVala, Helena
dc.contributor.authorNascimento, Maria S. J.
dc.date.accessioned2021-12-17T14:28:43Z
dc.date.available2021-12-17T14:28:43Z
dc.date.issued2020-03-04
dc.date.updated2021-12-12T18:04:09Z
dc.description.abstractHepatitis E virus (HEV) is an enteric RNA virus from the family Hepeviridae with five genotypes (genotypes 1–4 and 7) known to infect humans. HEV infection is known to have a zoonotic swine origin in industrialized countries. The role of pigs and wild boars as major reservoirs for human infection is today well-established; however, the list of new animal reservoirs is ever-expanding as new HEV strains are continuously being found in a broad host range. The recent detection of HEV in sheep stools brings concerns on the possibility of HEV transmission from these animals to humans, particularly in those occupationally exposed. The present work investigated the potential occupational risk of HEV infection in shepherds and sheep milk cheesemakers—workers occupationally exposed to ovine (WOEOs; N = 96)—from a region of the Centre of Portugal (‘Serra da Estrela’) based on the differences of anti-HEV IgG seroprevalence rates between these professionals and the general population (N = 192). The presence of HEV-specific antibodies in sheep (N = 90) from the same region was also evaluated. The HEV seroprevalence in WOEOs (29.3%) was found to be significantly higher (p = .0198) when compared with population controls (16.1%) which suggests an increased risk for HEV infection in these workers. HEV-specific antibodies were also found in 16.6% of the studied sheep showing that HEV circulates in these animals. Further studies are needed to confirm the zoonotic potential of sheep HEV.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMesquita, J. R., Santos-Ferreira, N., Ferreira, A. S., Albuquerque, C., Nóbrega, C., Esteves, F., Cruz, R., Vala, H., & Nascimento, M. S. J. (2020). Increased risk of hepatitis E virus infection in workers occupationally exposed to sheep. Transboundary and Emerging Diseases, 67(5), 1918–1921. https://doi.org/10.1111/tbed.13524pt_PT
dc.identifier.doi10.1111/tbed.13524pt_PT
dc.identifier.issn1865-1674
dc.identifier.issn1865-1682
dc.identifier.slugcv-prod-1734490
dc.identifier.urihttp://hdl.handle.net/10400.19/6939
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjecthepatitis E viruspt_PT
dc.subjectoccupational exposurept_PT
dc.subjectovinept_PT
dc.subjectsheeppt_PT
dc.subjectzoonosespt_PT
dc.titleIncreased risk of hepatitis E virus infection in workers occupationally exposed to sheeppt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1921pt_PT
oaire.citation.issue5pt_PT
oaire.citation.startPage1918pt_PT
oaire.citation.titleTransboundary and Emerging Diseasespt_PT
oaire.citation.volume67pt_PT
person.familyNameMesquita
person.familyNameDE SOUSA ALBUQUERQUE
person.familyNameNóbrega
person.familyNameEsteves
person.familyNameCruz
person.familyNameVala Correia
person.givenNameJoão
person.givenNameCARLOS MANUEL
person.givenNameCarmen
person.givenNameFernando
person.givenNameRita
person.givenNameHelena Maria
person.identifierB-6960-2016
person.identifier.ciencia-idCB1F-AFD2-529E
person.identifier.ciencia-id9B1E-D9AA-1C3F
person.identifier.ciencia-idD51F-A1CF-C925
person.identifier.ciencia-id6E19-A3CC-897E
person.identifier.ciencia-idA11E-DBFF-16E8
person.identifier.ciencia-id7A1E-E85E-FFA4
person.identifier.orcid0000-0001-8769-8103
person.identifier.orcid0000-0002-2297-0636
person.identifier.orcid0000-0003-3941-799X
person.identifier.orcid0000-0003-0589-0746
person.identifier.orcid0000-0002-5767-7835
person.identifier.orcid0000-0001-6829-4867
person.identifier.scopus-author-id35345458100
rcaap.cv.cienciaid7A1E-E85E-FFA4 | Helena Maria Vala Correia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationffcea03f-5943-43ae-aca6-a1b93b2b6134
relation.isAuthorOfPublication8a37caa0-40ca-4f15-b8d7-11bb6f4f4515
relation.isAuthorOfPublication0b9969e9-920a-4572-8fb1-73abb2fa3988
relation.isAuthorOfPublication93d688a9-9716-444c-9d08-fdca593d630d
relation.isAuthorOfPublication8e60c18a-9c3f-4b0e-be9e-4378ebc1594e
relation.isAuthorOfPublicationcdc3d2e2-df06-40ed-8900-1ecbc8a06c8a
relation.isAuthorOfPublication.latestForDiscoveryffcea03f-5943-43ae-aca6-a1b93b2b6134

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
42_Hepatitis_E_virus_WOEO_provas.pdf
Size:
670.54 KB
Format:
Adobe Portable Document Format
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.82 KB
Format:
Item-specific license agreed upon to submission
Description: