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Critérios de diagnóstico da Síndrome de Brugada. Podemos melhorar?

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dc.contributor.authorSantos, Luís Ferreira
dc.contributor.authorPereira, Telmo
dc.contributor.authorRodrigues, Bruno
dc.contributor.authorCorreia, Emanuel
dc.contributor.authorMoreira, Davide
dc.contributor.authorNunes, Luís
dc.contributor.authorCosta, António
dc.contributor.authorElvas, Luís
dc.contributor.authorMachado, José Carlos
dc.contributor.authorCastedo, Sérgio
dc.contributor.authorHenriques, Carla
dc.contributor.authorMatos, Ana
dc.contributor.authorSantos, Oliveira
dc.date.accessioned2017-10-04T10:52:26Z
dc.date.available2017-10-04T10:52:26Z
dc.date.issued2012
dc.description.abstractDiagnosis of Brugada syndrome (BS) currently requires documentation of a characteristic repolarization pattern (type 1 Brugada ECG). Mutations in the SCN5A gene, which codes for sodium channel Na(v) 1.5, are found in 38% of familial cases of BS. Sodium current dysfunction negatively affects the cardiac fast response action potential, particularly in atrial and ventricular myocytes and in the fast-conducting Purkinje system.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSantos, L. F., Pereira, T., Rodrigues, B., Correia, E., Moreira, D., Nunes, L.,...Santos, O. (2012). Critérios de diagnóstico da Síndrome de Brugada. Podemos melhorar? [Diagnostic criteria for the Brugada syndrome: can they be improved?]. Revista Portuguesa de Cardiologia, 31(5), 355–62. doi:10.1016/j.repc.2011.09.023pt_PT
dc.identifier.doi10.1016/j.repc.2011.09.023pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.19/4671
dc.language.isoporpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S2174204912000384pt_PT
dc.subjectSíndrome de Brugadapt_PT
dc.subjectBrugada Syndromept_PT
dc.subjectScore diagnósticopt_PT
dc.subjectDiagnostic scorept_PT
dc.subjectSCN5A genept_PT
dc.subjectSCN5Apt_PT
dc.titleCritérios de diagnóstico da Síndrome de Brugada. Podemos melhorar?pt_PT
dc.title.alternativeDiagnostic criteria for the Brugada syndrome: can they be improved?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage362pt_PT
oaire.citation.issue5pt_PT
oaire.citation.startPage355pt_PT
oaire.citation.titleRevista Portuguesa de Cardiologiapt_PT
oaire.citation.volume31pt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT

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