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Advisor(s)
Abstract(s)
A skin lesion from a 2,5 years male Perdigueiro, removed from the scapulo-humeral area of the left anterior limb, was submitted to the pathology service of the Escola Superior Agrária de Viseu. Macroscopicaly, the lesion corresponded to an ovoid and well-circunscribed mass, elevated above the skin surface, with 6,5x7,5x4cm. On cut section, a central cystic formation with fibrous capsule and several papillary growths that project into the lumen were observed.
Four 3 m sections were processed for routine histopathological diagnosis.
Microscopically, the central cyst was surrounded by areas of solid pattern, with numerous lobules subdivided by connective tissue stroma, and by intermingled areas of papillary growths.
The cells in both the papillary proliferations and solid area were arranged in nests and cords. In terms of morphology, at the periphery of the nests or cords, cells were basaloid lyke, round or polyhedrical, with an ovoid and hyperchromatic nuclei, and little cytoplasm, occasionally showing melanin granules. In the centre of these structures, spinous differentiation was observed, with more pale and abundant cytoplasm, frequently keratinized, and large pale nuclei. These cells revealed only mild pleomorphism. Dysqueratotic cells were also commonly found. A distinct feature was the absence of a transition zone between the basal and squamous cell types, which is very characteristic of the basosquamous carcinoma, an uncommon canine tumor, with features of both basal cell and squamous cell carcinoma.
It is the authors’ believe that the final diagnosis in this case is in fact basosquamous carcinoma, even taking in consideration that this was a young dog and that this kind of tumor had never been described in an autochthon dog
Description
Keywords
dog cutaneous neoplasia uncommon canine tumor squamous cell carcinoma
Citation
Vala H, Esteves F (2005) Um caso de carcinoma basoscamoso. III Congresso da Sociedade Portuguesa das Ciências Veterinárias. Estação Zootécnica Nacional, Vale de Santarém: 85