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Advisor(s)
Abstract(s)
Bovine Ocular Squamous Cell Carcinoma (OSCC) is a general designation for a group
of primary neoplasias of keratinocytes arising from ocular tissues, especially the lids and particularly the third eye lid. OSCC has been diagnosed all over the world with high prevalence, being the most common bovine tumour and the one causing the most significant economic losses (Hamir & Parry, 1980; Dennis et al., 1985, Heeney & Valli,
1985; Wilcock, 1993).
In Portugal, the frequency of these tumours is particularly high in the Azores, where in
S. Miguel Island a large number of cattle affected with OSCC is rejected for
consumption at slaughter. OSCC is the second most frequent neoplasia after urinary
bladder tumours, representing 21% of all cases of rejection due to neoplasia (Pinto et
al, 1996). Several reasons have been advanced to explain this situation namely the fact
that animals stay in pasture all year around, with a prolonged exposition to day light and
benefiting from few shelters. The ingestion of toxic plants present the pasture could also give rise to photosensitazation problems, either primary or due to hepatic toxicity, that could generate predisposing conditions to the development of OSCC.
Description
Keywords
BOSCC bovine Bovine Ocular Squamous Cell Carcinoma immunohistochemical techniques epidermal cell proliferation differentiation markers
Citation
Vala H, Fondevila D, Carvalho T, Pinto C, Peleteiro C, Pinho M, Ferrer L. Immunohistochemistry studies on bovine squamous cell carcinoma morphological characterization of epidermal cell proliferation and differentiation markers and characterization of cytokeratins. 1st International Symposium Research in Veterinary Science. Faculdade de Medicina Veterinária, Lisboa. 24-25 May 2001