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Abstract(s)
Introdução: Desde a identificação da bactĂ©ria Helicobacter Pylori (HP) por Marshall & Warren em 1982, e apĂłs sucessivas investigaçÔes, que esta infeção tem sido referenciada como um importante problema de saĂșde pĂșblica, afetando pessoas de todas as idades. Pelo menos metade da população em geral estĂĄ infetada verificando-se uma variabilidade geogrĂĄfica quanto Ă prevalĂȘncia dentro e entre paĂses de acordo com a geografia, etnia, idade e fatores socioeconĂłmicos. Esta bactĂ©ria, localizada na mucosa gĂĄstrica, associa-se a vĂĄrios fatores comportamentais, socioeconĂłmicos, ambientais e hĂĄbitos de higiene.
MĂ©todos: realizĂĄmos um estudo observacional, transversal e analĂtico com uma amostra comunitĂĄria de adultos dos concelhos de Viseu e SatĂŁo. A amostra final ficou constituĂda por 166 adultos, com idades compreendidas entre os 19 e os 92 anos de idade (mĂ©dia de 46,96±3,17 anos) sendo a maioria do gĂ©nero feminino (56,6%).
Os dados foram recolhidos atravĂ©s de um questionĂĄrio auto-aplicado com questĂ”es referentes a aspetos sociodemogrĂĄficos, agregado familiar, hĂĄbitos diĂĄrios e estilos de vida. A infeção por HP foi identificada com recurso ao teste respiratĂłrio da urease. O teste foi realizado pela manhĂŁ, apĂłs pelo menos 6 horas de jejum. A dispepsia funcional foi avaliada com recurso ao questionĂĄrio ROMA III, validado para a população portuguesa. A anĂĄlise estatĂstica realizou-se com recurso ao programa estatĂstico SPSS 23.0. As prevalĂȘncias expressas em proporçÔes e comparadas pelo teste qui-quadrado. As associaçÔes foram calculadas com recurso ao Odds Ratio (OR), com intervalos de confiança de 95% (IC 95%).
Resultados: A prevalĂȘncia de HP em adultos foi de 48,8% (50,0% no sexo feminino e 47,2% no sexo masculino). EncontrĂĄmos percentagens maiores para o sexo feminino, idades †50 anos, estado civil de casado, para um maior nĂșmero de irmĂŁos e em pessoas que se encontravam no ativo, contudo sem diferenças estatĂsticas. Apenas se verificou associação com o ano de escolaridade †9Âș ano (OR=1,31; IC95% 1,02-1,87). Quanto aos fatores alimentares, estilos de vida e condiçÔes de higiene, apenas apurĂĄmos diferenças significativas para as variĂĄveis menor frequĂȘncia de lavagem das mĂŁos antes de ir ĂĄ casa de banho (p=0,02) e o consumo de ĂĄgua de poço (p=0,05). A prevalĂȘncia de dispepsia funcional foi de 39,8%; da sĂndrome enfartamento pĂłs-prandial de 66,3%, e a prevalĂȘncia da sĂndrome da dor epigĂĄstrica foi de 71,1%. O estado civil âcasadoâ apresentou uma associação de proteção com a dispepsia funcional (OR=0,49 IC95% 0,26-0,93). NĂŁo encontrĂĄmos associação entre o H. pylori e a dispepsia funcional.
ConclusĂ”es: Podemos concluir que quase metade dos adultos apresenta infeção por HP e os fatores associados Ă infeção por HP foram a escolaridade †9Âș ano, menor frequĂȘncia de lavagem das mĂŁos antes de ir Ă casa de banho e o consumo de ĂĄgua ser de poço. Com a dispepsia funcional, 39,8% dos indivĂduos apresentaram esta condição e ser casado diminuĂa o risco de dispepsia funcional. Na presença investigação a dispepsia funcional e o HP nĂŁo se associaram. Palavras chave: Helicobacter pylori, dispepsia funcional, adultos, epidemiologia, prevalĂȘncia, fatores de risco.
Abstract: Introduction: Since the identification of the Helicobacter Pylori (HP) bacterium by Marshall & Warren in 1982, and after several investigations, this infection has been referred as a major public health issue, affecting people of all ages. At least half of the general population is infected with geographic variability in prevalence within and across countries according to geographic, ethni-cal, age and socioeconomic factors. This bacterium, located in the gastric mucosa, is associated with several behavioral, socioeconomic, environmental and hygiene habits. Methods: We carried out an observational, cross-sectional and analytical study with a communi-ty-based sample of adults from the city of Viseu and the town of Satão, Portugal. The final sam-ple consisted of 166 adults, aged between 19 and 92 years (mean of 46.96 ± 3.17 years), the ma-jority of the female gender (56.6%). Data were collected through a self-administered question-naire with questions regarding sociodemographic aspects, household, daily habits and lifestyles. HP infection was identified using the urease respiratory test. The test was performed in the morn-ing after at least 6 hours of fasting. Functional dyspepsia was assessed using the ROMA III ques-tionnaire, validated for the Portuguese population. Statistical analysis was performed using the statistical program SPSS 23.0. The prevalences were expressed in proportions and compared by the chi-square test. The associations were calculated using Odds Ratio (OR), with 95% confi-dence intervals (95% CI). Results: The prevalence of HP in adults was 48.8% (50.0% in females and 47.2% in males). We found higher percentages among the female gender, ages †50 years, marital status, for a greater number of siblings and in people who were in the active, yet without statistical differences. There was only association with the year of schooling †9th year (OR = 1.31, 95% CI 1.02-1.87). Re-garding food factors, lifestyles and hygiene conditions, we only found significant differences for the variables less frequency of hand washing before going to the bathroom (p = 0.02) and well water consumption (p = 0.05). The prevalence of functional dyspepsia was 39.8%, postprandial infarction syndrome was 66.3% and the prevalence of epigastric pain syndrome was 71.1%. Mar-ital status had a protective association with functional dyspepsia (OR = 0.49, 95% CI 0.26-0.93). We found no association between H. pylori and functional dyspepsia. Conclusions: We can conclude that almost half of the adults present HP infection and the factors associated with HP infection were schooling †9th year, less frequency of hand washing before going to the toilet and well water consumption. With functional dyspepsia, 39.8% of the individ-uals presented this condition and being married reduced the risk of functional dyspepsia. In the present research, functional dyspepsia and HP were not associated. Keywords: Helicobacter pylori, Functional dyspepsia, adults, epidemiology, prevalence, risk factors.
Abstract: Introduction: Since the identification of the Helicobacter Pylori (HP) bacterium by Marshall & Warren in 1982, and after several investigations, this infection has been referred as a major public health issue, affecting people of all ages. At least half of the general population is infected with geographic variability in prevalence within and across countries according to geographic, ethni-cal, age and socioeconomic factors. This bacterium, located in the gastric mucosa, is associated with several behavioral, socioeconomic, environmental and hygiene habits. Methods: We carried out an observational, cross-sectional and analytical study with a communi-ty-based sample of adults from the city of Viseu and the town of Satão, Portugal. The final sam-ple consisted of 166 adults, aged between 19 and 92 years (mean of 46.96 ± 3.17 years), the ma-jority of the female gender (56.6%). Data were collected through a self-administered question-naire with questions regarding sociodemographic aspects, household, daily habits and lifestyles. HP infection was identified using the urease respiratory test. The test was performed in the morn-ing after at least 6 hours of fasting. Functional dyspepsia was assessed using the ROMA III ques-tionnaire, validated for the Portuguese population. Statistical analysis was performed using the statistical program SPSS 23.0. The prevalences were expressed in proportions and compared by the chi-square test. The associations were calculated using Odds Ratio (OR), with 95% confi-dence intervals (95% CI). Results: The prevalence of HP in adults was 48.8% (50.0% in females and 47.2% in males). We found higher percentages among the female gender, ages †50 years, marital status, for a greater number of siblings and in people who were in the active, yet without statistical differences. There was only association with the year of schooling †9th year (OR = 1.31, 95% CI 1.02-1.87). Re-garding food factors, lifestyles and hygiene conditions, we only found significant differences for the variables less frequency of hand washing before going to the bathroom (p = 0.02) and well water consumption (p = 0.05). The prevalence of functional dyspepsia was 39.8%, postprandial infarction syndrome was 66.3% and the prevalence of epigastric pain syndrome was 71.1%. Mar-ital status had a protective association with functional dyspepsia (OR = 0.49, 95% CI 0.26-0.93). We found no association between H. pylori and functional dyspepsia. Conclusions: We can conclude that almost half of the adults present HP infection and the factors associated with HP infection were schooling †9th year, less frequency of hand washing before going to the toilet and well water consumption. With functional dyspepsia, 39.8% of the individ-uals presented this condition and being married reduced the risk of functional dyspepsia. In the present research, functional dyspepsia and HP were not associated. Keywords: Helicobacter pylori, Functional dyspepsia, adults, epidemiology, prevalence, risk factors.
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Keywords
Adulto Dispepsia Factores de risco Helicobacter pylori InfecçÔes por helicobacter PrevalĂȘncia Adult Dyspepsia Helicobacter infections Prevalence Risk factors