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Quercus spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review

2023-07Journal article Open access
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dc.contributor.authorOliveira, Paula
dc.contributor.authorMedeiros-Fonseca, Beatriz
dc.contributor.authorVasconcelos-Nóbrega, Carmen
dc.contributor.authorAlvarado, Antonieta
dc.contributor.authorPires, Maria
dc.contributor.authorVala, Helena
dc.contributor.authorBarros, Ana
dc.contributor.authorFaustino-Rocha, Ana
dc.date.accessioned2023-11-13T15:13:41Z
dc.date.available2023-11-13T15:13:41Z
dc.date.issued2023-07
dc.date.updated2023-11-12T20:16:03Z
dc.description.abstractAcorns have traditionally been used in the human diet and for the treatment of specific diseases. Therefore, the present study performed a systematic review of studies which investigated the effects of Quercus spp. extracts in cancer prevention and treatment. A systematic literature search was performed for original records which addressed the anticancer effects of Quercus spp. extract in in vitro and in vivo cancer models. Body composition, food consumption, tumor development and/or toxicity were evaluated in in vivo studies, while cytotoxicity was evaluated in in vitro studies. Few studies and low sample sizes presented a challenge in the drawing of solid conclusions. Overall, the results suggested a positive impact of Quercus spp. extract, by reducing cancer development. Therefore, more studies with different cancer cell lines and animal models to address the efficacy of the acorn extracts in several types of cancer are required. Furthermore, the effects of acorn flour, incorporated in the diet, in an animal model of mammary cancer should be evaluated.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationOliveira, P. A., Medeiros-Fonseca, B., Vasconcelos-Nóbrega, C., Alvarado, A., Pires, M. J., Vala, H., Barros, A. I. R. N. A., & Faustino-Rocha, A. I. (2023). Quercus spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review. Molecular Medicine Reports, 28(3), 175. https://doi.org/10.3892/mmr.2023.13062pt_PT
dc.identifier.doi10.3892/mmr.2023.13062pt_PT
dc.identifier.issn1791-2997
dc.identifier.issn1791-3004
dc.identifier.slugcv-prod-3394369
dc.identifier.urihttp://hdl.handle.net/10400.19/8020
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectQuercus spppt_PT
dc.subjectacornpt_PT
dc.subjectextractpt_PT
dc.subjectin vitropt_PT
dc.subjectin vivopt_PT
dc.subjectoakpt_PT
dc.subjectoncologypt_PT
dc.titleQuercus spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue3pt_PT
oaire.citation.startPage175pt_PT
oaire.citation.titleMolecular Medicine Reportspt_PT
oaire.citation.volume28pt_PT
person.familyNamede Sousa Oliveira
person.familyNameVala Correia
person.givenNameMaria Paula
person.givenNameHelena Maria
person.identifier.ciencia-idC412-3525-557A
person.identifier.ciencia-id7A1E-E85E-FFA4
person.identifier.orcid0000-0002-6376-1099
person.identifier.orcid0000-0001-6829-4867
rcaap.cv.cienciaid7A1E-E85E-FFA4 | Helena Maria Vala Correia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication06a0a05e-b74b-47f8-9d0e-bc17e329b123
relation.isAuthorOfPublicationcdc3d2e2-df06-40ed-8900-1ecbc8a06c8a
relation.isAuthorOfPublication.latestForDiscovery06a0a05e-b74b-47f8-9d0e-bc17e329b123

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