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A case of vascular tumour mimicking lymphangioma

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dc.contributor.authorVala, Helena
dc.contributor.authorMega, Cristina
dc.contributor.authorSantos, C.
dc.contributor.authorCruz, Rita
dc.contributor.authorSantos, M.
dc.contributor.authorEsteves, Fernando
dc.contributor.authorNóbrega, Carmen
dc.contributor.authorMesquita, João
dc.date.accessioned2016-02-17T15:35:48Z
dc.date.available2016-02-17T15:35:48Z
dc.date.issued2015
dc.description.abstractIntroduction Sarcomas, particularly vascular tumours, can mimic other neoplastic conditions or even inflammatory diseases. Objectives The authors describe an unusual case of vascular tumour, histologically overlapping with benign lymphangioma and liposarcoma. Medical History A 8 year old Shar Pei male dog was presented with a subcutaneous nodule in the chest, measuring 3x2 cm. Material and Methods The sample was fixed in 10 % buffered formalin solution and processed for routine histopathological diagnosis with Haematoxylin and Eosin. A standard Streptavidin-Biotin Complex technique for immunohistochemical evaluation was also performed, using a Polyclonal Rabbit Anti-Human Von Willebrand Factor. Results Macroscopic examination revealed a well circumscribed nodule with homogeneous and brownish appearance and moderate consistency on a cut surface. Microscopic examination revealed clefts and variably-sized vascular spaces, lined by a single layer of spindle cells, with round-to-oval nuclei, small or indistinct nucleoli, small amount of eosinophilic cytoplasm, with endothelial appearance – areas like hemangiosarcoma, interspersed with areas, where these cells appeared to grow directly on thick bundles of dermal collagen, occasionally with erythrocytes – areas like lymphangioma. The stroma was also interspersed with vacuolar cells – areas like liposarcoma. No mitotic figures were seen, however, the presence of very rich cellular areas, with more prominent cells revealing pleomorphism and anisocariosis, were more favour to malignancy Conclusion The authors suggested the diagnosis of vascular neoplasia with unusual features, based on the histopathological diagnosis and immunohistochemistry results, and submit to the discussion, especially for assessment of histological grade and prognosis.pt_PT
dc.identifier.citationVala H, Mega A, Santos C, Cruz R, Santos M, Esteves F, Nóbrega C, Mesquita JR. (2015). A case of vascular tumour mimicking lymphangioma. Abstract book of the XX Meeting of the Portuguese Society of Animal Pathology. Fish Pathology: 15pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.19/3063
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationIPV, CI&DETS, FCT and QREN/FEDER (Ovislab ICT-2013-05-004-5314 ID-64757)pt_PT
dc.subjectvascular tumourspt_PT
dc.subjectSarcomaspt_PT
dc.subjectcaninept_PT
dc.titleA case of vascular tumour mimicking lymphangiomapt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.titleAbstract book of the XX Meeting of the Portuguese Society of Animal Pathology. Fish Pathologypt_PT
oaire.citation.volume15pt_PT
person.familyNameVala Correia
person.familyNameMega
person.familyNameCruz
person.familyNameEsteves
person.familyNameNóbrega
person.familyNameMesquita
person.givenNameHelena Maria
person.givenNameCristina
person.givenNameRita
person.givenNameFernando
person.givenNameCarmen
person.givenNameJoão
person.identifierB-6960-2016
person.identifier.ciencia-id7A1E-E85E-FFA4
person.identifier.ciencia-idA11E-DBFF-16E8
person.identifier.ciencia-id6E19-A3CC-897E
person.identifier.ciencia-idD51F-A1CF-C925
person.identifier.ciencia-idCB1F-AFD2-529E
person.identifier.orcid0000-0001-6829-4867
person.identifier.orcid0000-0002-9913-875X
person.identifier.orcid0000-0002-5767-7835
person.identifier.orcid0000-0003-0589-0746
person.identifier.orcid0000-0003-3941-799X
person.identifier.orcid0000-0001-8769-8103
person.identifier.scopus-author-id35345458100
rcaap.rightsrestrictedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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