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Advisor(s)
Abstract(s)
Introduction
Neoplasms involving the optic nerve are rare. Intraorbital meningiomas, the most common tumour of the optic nerve, represent only 3% of all meningiomas in dogs, so few data exists to predict its symptoms and biologic behaviour.
Objectives
The authors describe and submit for discussion, a rare case of retrobulbar meningioma, in particular for assessment of histological grade and prognosis.
Medical History
A 10 year old Labrador Retriever male dog was presented for complaints of swelling and purulent discharge of the right eye. The animal had exophthalmos, protrusion of the third eyelid, chemosis, deep corneal ulceration and no pupillary light reflex. Exophthalmos due to a retrobulbar mass was diagnosed after physical, ophthalmic and ultrasound examination.
Material and Methods
The sample was fixed in 10 % buffered formalin solution, processed for routine histopathological diagnosis and a standard Streptavidin-Biotin Complex technique for immunohistochemical evaluation was also performed.
Results
Macroscopic examination revealed a conic mass, located in the retrobulbar portion of the optic nerve, adjacent to the posterior aspect of the globe with homogeneous, lobulated and whitish appearance and firm consistency.
Microscopic examination revealed spindloid cells, with round-to-oval, finely stippled nuclei, small or indistinct nucleoli, moderate amount of eosinophilic cytoplasm, arranged in concentric whorls around capillaries, separated by interlacing fascicles, with small amount of well vascularized, collagenous stroma.
Conclusion
The authors suggested the diagnosis of transitional meningioma, based on the histopathological diagnosis and immunohistochemistry results.
Description
Keywords
Neoplasms optic nerve canine transitional meningioma dog
Citation
Vala H, Mega A, Santos C, Cruz R, Nóbrega C, Mesquita JR, Esteves F, Vieira F, Ferraz A (2013). A rare case of retrobulbar neoplasia. Revista Portuguesa de Ciências Veterinárias. 108 (585-586): 73.