Browsing by Author "Mesquita, J. R."
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- Breves considerações sobre a evolução, impacto e profilaxia do parvovírus caninoPublication . Costa, M.; Nóbrega, C.; Mega, A.; Esteves, F.; Cruz, R.; Santos, C.; Vala, Helena; Santos, M.; Mesquita, J. R.A família Parvoviridae está dividida em duas subfamílias. A subfamília Parvovirinae, que inclui os vírus que afectam vertebrados e a subfamília Densovirinae, que contém os vírus que afectam insectos (MacLachlan & Dubovi, 2011). Dentro da subfamília Parvovirinae foram definidos cinco géneros: Erytrovírus, Dependovírus, Parvovírus, Amdovírus e Bocavírus.
- A case of biliary cystadenoma in a geriatric cat.Publication . Vala, Helena; Nóbrega, C.; Ribeiro, A.; Mega, C.; Oliveira, A. L.; Santos, C.; Coelho, C.; Esteves, F.; Cruz, R.; Mesquita, J. R.A 9–year-old male European cat was referred for clinical examination with a history of anorexia, apathy and mild dehydration. Neurological exam revealed anisocoria and decreased pupillary reflex. Ultrasound examination of the abdomen suggested the presence of a mesenteric mass and several areas of renal and hepatic lesions. Renomegaly was also observed. Samples of organs were submitted to the pathology service of the Superior Agrarian School of Viseu. Macroscopic exam of the liver showed several prominent whitish areas that, on cut section, revealed multilocular cystic appearance with greenish colour in some of them. The mesenteric mass, of friable consistency, showed 5,5 x4,4x3,5 cm On cut section this mass revealed whitish areas of soft consistency that alternated with hemorrhagic areas. The kidneys showed an white, irregular surface, and also in one of them a corical prominent nodule was seen. Several sections were processed for routine histopathological diagnosis. Microscopic exam revealed that the mesenteric mass corresponded to a tumour of lymphoid cells. Cells were large, with scanty cytoplasm, euchromatic round nucleus with prominent central nucleoli, high mitotic count and moderate pleomorphism invading surrounding adipose tissue. The same type of cells was observed in the liver and kidneys. Based on these results, a lymphoma with renal and hepatic metastases was diagnosed in the mesenteric mass. Concomitantly, microscopic examination of the liver showed hepatocyte vacuolation and trabecular disorganization, with multiple cystic cavities lined by an epithelium of cubic or squamous type, showing fine fibrovascular tissue stroma. The cuboidal epithelial cells presented a moderate amount of pale eosinophilic cytoplasm, round or oval nucleus, vesicular, oriented centrally and with small or inapparent nucleoli. Based on these results, the diagnosis of neoplasia derived from biliary epithelium, was established. The differential diagnosis to be considered on this case were colangioma and biliary cystadenoma. The definitive diagnosis of biliary cystadenoma was established, based on the presence of multiple cystic cavities, disseminated by the hepatic parenchyma. According to previous statements, it was concluded that in spite of its rare occurrence, this is a case of biliary cystadenoma.
- Feline Calicivirus: unveiling data on viral inactivationPublication . Lemos, M.; Nóbrega, C.; Vala, Helena; Mesquita, J. R.Feline Calicivirus (FCV) is an important and widespread virus of the feline population. As a member of the Caliciviridae family, FCV mutates readily in nature, and this has resulted in the recent emergence of a highly virulent haemorrhagic systemic strain. Despite the increased concern about this feline pathogen, little is still known on potential FCV virucidal compounds. On the other hand several experiments on the inactivation behaviour of various surface disinfectants have used FCV as a surrogate to monitor norovirus survival in order to minimize their impact on public health. This has led to a considerable number of studies generating a huge amount of data on FCV inactivation. These findings are presented here and may be useful to veterinary nurses who can improve their practice by minimizing FCV transmission.
- Feline lungworm infection. An emerging concern?Publication . Vala, Helena; Esteves, F.; Santos, C.; Mega, A.C.; Coelho, C.; Nóbrega, C.; Cruz, C.; Mesquita, J. R.Infectious feline upper respiratory tract disease is very common and Aelurostrongylus abstrusus is the most often diagnosed parasitic cause, although clinical signs may go unnoticed and diagnosis is challenging as it has several limitations. Noting that more cases have been recorded in recent years, the authors, in the present work, describe in detail the features of five cases of Aelurostrongylus abstrusus registered in their work and influence area, to alert animal health professionals to this emerging concern.
- Gastrocanis – an internet-based epidemiologic surveillance tool.Publication . Sacramento R; Santos, C.; Vala, Helena; Esteves, F.; Oliveira, A. L.; Cruz, R.; Mega, A. C.; Nóbrega, C.; Mesquita, J. R.
- he Zoonotic Event of Leishmaniasis in Portugal: a Public Health Concern.Publication . Gouveia, A.; Santos, C; Vala, Helena; Esteves, F.; Oliveira, A. L.; Cruz, R.; Mega, A. C.; Nóbrega, C.; Mesquita, J. R.
- Human and animal dermatophytosis: is it a real Public Health issue?.Publication . Matos, A.; Santos, C.; Vala, Helena; Esteves, F.; Oliveira, A. L.; Cruz, R.; Mega, A. C.; Nóbrega, C.; Mesquita, J. R.
- Implementation of a canine gastroenteritis real-time participation and monitoring system: a possibly valuable epidemiological tool.Publication . Sacramento, R.; Santos, C.; Vala, Helena; Esteves, F.; Oliveira, A. L.; Cruz, R.; Mega, A. C.; Nóbrega, C.; Mesquita, J. R.
- Leishmaniasis in Portugal: the Veterinary Nursing as a part of the solution.Publication . Gouveia A; Santos, C.; Vala, Helena; Esteves, F.; Oliveira, A. L.; Cruz, R.; Mega, A. C.; Nóbrega, C.; Mesquita, J. R.
- Melanocytic Tumour in a Black Sheep never exposed to Ultraviolet RadiationPublication . Vala, Helena; Pópulo, H.; Mesquita, J. R.; Esteves, F.; Santos, C.; Soares, P.; Lopes, J. M.A slow growing progressive head skin tumour in a 6-year-old “Serra da Estrela” (black variety) male sheep without previous history of ultraviolet radiation exposure or illness is described. The tumour consisted of a large (5.4cm) irregular mass subdivided into two polypoid-like regions and small alternating pigmented and non-pigmented areas in the surrounding thick epidermis. By light microscopy the tumour disclosed morphologic and immunohistochemistry features consistent with a melanocytoma type tumour, without signs of vascular and perineural invasion. The tumour cells contained Masson-Fontana positive pigment, expressed S100 protein and vimentin, and display a low proliferative (Ki67<1%) labelling index. No metastases were found in the autopsy study. Analyses of the homologous regions of the hotspot mutational exons of BRAF and NRAS (the most often mutated genes in human melanocytic tumours) did not reveal alterations, but silent polymorphic variations, and no variation was observed in GNAQ gene sequence, that is found mutated in human melanocytomas. In summary, we report the phenotypic and genotypic features of, as far as we are aware, the first case of a head skin melanocytoma type tumour with low-grade malignant potential in a black sheep non-exposed to environmental radiation.