Percorrer por autor "Nóbrega, C."
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- Breves considerações sobre a evolução, impacto e profilaxia do parvovírus caninoPublication . Costa, M.; Nóbrega, C.; Mega, A.; Esteves, F.; Cruz, R.; Santos, C.; Vala, Helena; Santos, M.; Mesquita, J. R.A família Parvoviridae está dividida em duas subfamílias. A subfamília Parvovirinae, que inclui os vírus que afectam vertebrados e a subfamília Densovirinae, que contém os vírus que afectam insectos (MacLachlan & Dubovi, 2011). Dentro da subfamília Parvovirinae foram definidos cinco géneros: Erytrovírus, Dependovírus, Parvovírus, Amdovírus e Bocavírus.
- Canine hair follicular tumours: a retrospective studyPublication . Vala, Helena; Brito, M.; Esteves, Fernando; Cruz, R.; Santos, C.; Mega, A.C.; Nóbrega, C.; Mesquita, JR; Lemos, CHair follicular tumours in dog comprise a large and heterogeneous group of neoplasms that display morphological features resembling one or several portions of the normal hair follicle which constitute a huge effort for its diagnosis. Histopathological evaluation is required to better characterize the different types of canine hair follicular tumours, in order to better understand its biological behaviour and to collaborate with the daily clinical practice. Thus, a retrospective, cross-sectional descriptive study was carried out with goal of analyse its frequency and characteristics, in order to contribute to a better understanding of this vast group of tumours. As main results the authors verified a higher incidence of follicular tumours in male dogs, being the most frequent types diagnosed trichoepithelioma, followed by, trichoblastoma, infundibular keratinizing acanthoma and pilomatricoma and the average age of dogs was 8.76 years. Also, malignant tumours represented 31.6% of all canine hair follicular tumours diagnosed (n= 114).
- A case of biliary cystadenoma in a geriatric cat.Publication . Vala, Helena; Nóbrega, C.; Ribeiro, A.; Mega, C.; Oliveira, A. L.; Santos, C.; Coelho, C.; Esteves, F.; Cruz, R.; Mesquita, J. R.A 9–year-old male European cat was referred for clinical examination with a history of anorexia, apathy and mild dehydration. Neurological exam revealed anisocoria and decreased pupillary reflex. Ultrasound examination of the abdomen suggested the presence of a mesenteric mass and several areas of renal and hepatic lesions. Renomegaly was also observed. Samples of organs were submitted to the pathology service of the Superior Agrarian School of Viseu. Macroscopic exam of the liver showed several prominent whitish areas that, on cut section, revealed multilocular cystic appearance with greenish colour in some of them. The mesenteric mass, of friable consistency, showed 5,5 x4,4x3,5 cm On cut section this mass revealed whitish areas of soft consistency that alternated with hemorrhagic areas. The kidneys showed an white, irregular surface, and also in one of them a corical prominent nodule was seen. Several sections were processed for routine histopathological diagnosis. Microscopic exam revealed that the mesenteric mass corresponded to a tumour of lymphoid cells. Cells were large, with scanty cytoplasm, euchromatic round nucleus with prominent central nucleoli, high mitotic count and moderate pleomorphism invading surrounding adipose tissue. The same type of cells was observed in the liver and kidneys. Based on these results, a lymphoma with renal and hepatic metastases was diagnosed in the mesenteric mass. Concomitantly, microscopic examination of the liver showed hepatocyte vacuolation and trabecular disorganization, with multiple cystic cavities lined by an epithelium of cubic or squamous type, showing fine fibrovascular tissue stroma. The cuboidal epithelial cells presented a moderate amount of pale eosinophilic cytoplasm, round or oval nucleus, vesicular, oriented centrally and with small or inapparent nucleoli. Based on these results, the diagnosis of neoplasia derived from biliary epithelium, was established. The differential diagnosis to be considered on this case were colangioma and biliary cystadenoma. The definitive diagnosis of biliary cystadenoma was established, based on the presence of multiple cystic cavities, disseminated by the hepatic parenchyma. According to previous statements, it was concluded that in spite of its rare occurrence, this is a case of biliary cystadenoma.
- A case of intense and multiple parasitic infestation in a wild pigeon (Columbia livia).Publication . Coelho, C.; Nóbrega, C.; Santos, C.; Cruz, R.; Mesquita, J.; Oliveira, A. L.; Mega, A. C.; Esteves, F.; Vala, HelenaIntroduction The prevalence of parasitic diseases in poultry seems to have significantly reduced due not only to the intensive production system but also to the improving conditions of hygiene and management practiced. However, parasitic diseases continue to have great importance in traditional production systems and production systems in the outdoors, contributing significantly to productivity decline of these farms. The pigeon (Columbia livia), a specie produced with outdoors access is more susceptible to infestations. The growing population of wild pigeons in urban areas can be decisive in the infestation of domestic pigeons, since they share the same places and their sanitary control is more difficult. Objectives The aim of this work is to describe a case of a pigeon (Columbia livia) with an intense parasitic infestation, this being the cause of death, with common parasitic species and other less frequent. Material and Methods A cadaver of a pigeon was submitted to the necropsy of Anatomic Pathology Laboratory of the Agrarian Superior School of Viseu, a detailed post mortem examination was carried out and samples were taken. All samples were fixed in 10% neutral-buffered formalin, for a maximum of 48 hours and processed following the routine histopathological technique. Results Gross examination lesions revealed rounded red lesions in the proventriculus serosa and lung congestion. Microscopic examination confirmed severe lung congestion, with hemosiderosis and the presence of numerous nematodes in cross section, discussing the hypothesis that it might be a case of Cyathostoma bronchialis (Muehlig 1884), taking into account the location or, less likely, an erratic parasite in histotropic migration phase. Eggs observed at this location had thick shell, oval shape, some were embryonated and 35-40 μm in length by 20-25 μm in width. In the lumen of the proventriculus glands, nematodes in cross section were also observed, noting numerous barrel-shaped eggs, embryonated larvae, oval poles and 55 mm in length by 25 mm in width, apparently compatible with parasites of the genus Tetrameres. Conclusion The high parasitic infestation of the wild pigeon specimen subjected to necropsy, with several, common and uncommon, species of parasites, the severity of lesions, leading to death of the animal, as well as the fact that infected wild birds favoring the spread of the parasite to the domestic pigeons and other poultry production, consisting of a major concern for producers, justifies the study of isolated cases, even constituting an epidemiological alert for the regions where they appear.
- Cuidados de enfermagem em timpanismoPublication . Oliveira, J.; Oliveira, J.; Rego, A.; Valente, A.; Nascimento, R.; Vala, Helena; Mesquita, J.; Nóbrega, C.O timpanismo ruminal designa-se pela acumulação excessiva de gases e por vezes fluidos no retículo-rúmen, incapazes de serem eliminados pelo organismo, o que resulta no aumento anormal do abdómen (Radostits et al, 2007). Afecta ruminantes e é uma situação que pode desenvolver-se rapidamente e pôr em risco a vida do animal (Streeter, 2009). Este estudo sintetiza a etiologia, o diagnóstico, o tratamento e aconselhamento que é aplicável a esta patologia, procurando evidenciar o papel do enfermeiro veterinário em cada um dos parâmetros apresentados.
- Ear Mites: Tackling a Persistent ProblemPublication . Neves, A.; Mesquita, J.; Vala, Helena; Nóbrega, C.A several number of mites have been associated with ear problems, namely otitis externa (Scott et al., 2001). Fifty percent or more of all otitis, in cats, and 10%, in dogs, are thought to be caused by ear mites (Sotiraki et al., 2001; Mueller, 2008). Very common in pets, ear mites can be a serious problem. The most common mite is, undoubtedly, Otodectes cynotis, but there are some other mites that can also be found in the ear canal, includding Demodex canis, Demodex cati, Sarcoptes scabiei, Notoedres cati, among others (Cordero del Campillo et al., 1999; Blot et al., 2003; Engler, 2007). Frequently, ear mites can be the initiating factor of the otitis externa. The mechanical irritation, caused by their presence inside the ears, may lead to a higher activity of ceruminal glands and, consequently, the establishment of a favorable environment for secondary infections, caused by bacteria or fungi (August (1988) cited by Souza et al. (2008). These secondary infections and the animal’s individual response may perpetuate and induce the progression of the initial disease (Scott et al., 2001). It was established that the number of mites necessary to promote disease can be very low (only about two to three) triggering an Arthus-type and/or an immediate-type hypersensitivity reaction (Scott et al., 2001; Sotiraki et al., 2001; Angus, 2004). It has been reported that young animals tend to be more susceptible to ear mites than adult ones (Blot et al., 2003; Mueller, 2007; Mueller, 2008; Lefkaditis et al., 2009).
- Effect of chronic therapy with chaethomellic acid A on renal fibrosis in 5/6 nephrectomized rats: A preliminary studyPublication . Nogueira, A.; Vala, Helena; Nóbrega, C.; Pires, C. A.; Colaço, B.; Oliveira, P. A.; Pires, M. J.Objective: The high prevalence of chronic kidney disease underscores the failure to provide therapies to effectively halt, prevent, and/or reverse renal fibrosis. Thus, the aim of this study was to evaluate the effect of chronic treatment with chaethomellic acid A (CA) on renal fibrosis associated to 5/6 nephrectomy. Methods: Male Wistar rats were subjected to 5/6 nephrectomy (RMR) or sham-operated (SO). One week after surgery, rats were placed in four experimental groups: RMR: rats without treatment (n=13); RMR+CA: rats treated with CA (n=13); SO: rats without treatment (n=13); SO+CA: rats treated with CA (n=13). CA was intraperitoneally administered in a dose of 0.23 µg/Kg three times a week for six months. Renal samples were scored for the following lesions: glomerulosclerosis, interstitial fibrosis, arteriolosclerosis and interstitial inflammation. Results: Animals from the SO and SO+CA groups presented no kidney histological changes. Glomerulosclerosis, interstitial fibrosis and arteriolosclerosis scores were significantly lower (p< 0.001) in RMR+CA group when compared with RMR group. There were no significantly differences in interstitial inflammation score between RMR+CA and RMR groups. Conclusions: This preliminary data suggests that pharmacological inhibition of Ras (small GTPase proteins) activation may be a future strategy in the prevention of renal fibrosis.
- Feline Calicivirus: unveiling data on viral inactivationPublication . Lemos, M.; Nóbrega, C.; Vala, Helena; Mesquita, J. R.Feline Calicivirus (FCV) is an important and widespread virus of the feline population. As a member of the Caliciviridae family, FCV mutates readily in nature, and this has resulted in the recent emergence of a highly virulent haemorrhagic systemic strain. Despite the increased concern about this feline pathogen, little is still known on potential FCV virucidal compounds. On the other hand several experiments on the inactivation behaviour of various surface disinfectants have used FCV as a surrogate to monitor norovirus survival in order to minimize their impact on public health. This has led to a considerable number of studies generating a huge amount of data on FCV inactivation. These findings are presented here and may be useful to veterinary nurses who can improve their practice by minimizing FCV transmission.
- Feline lungworm infection. An emerging concern?Publication . Vala, Helena; Esteves, F.; Santos, C.; Mega, A.C.; Coelho, C.; Nóbrega, C.; Cruz, C.; Mesquita, J. R.Infectious feline upper respiratory tract disease is very common and Aelurostrongylus abstrusus is the most often diagnosed parasitic cause, although clinical signs may go unnoticed and diagnosis is challenging as it has several limitations. Noting that more cases have been recorded in recent years, the authors, in the present work, describe in detail the features of five cases of Aelurostrongylus abstrusus registered in their work and influence area, to alert animal health professionals to this emerging concern.
- Gastrocanis – an internet-based epidemiologic surveillance tool.Publication . Sacramento R; Santos, C.; Vala, Helena; Esteves, F.; Oliveira, A. L.; Cruz, R.; Mega, A. C.; Nóbrega, C.; Mesquita, J. R.